Fat Tony is a cancer on this fair city. He is the cancer, and I am the... uh, what cures cancer?— Wiggum
Framegrabs from the Season 16 episode, Sleeping With the Enemy. When Marge realises that Bart and Lisa dislike her mothering them, she takes Nelson Muntz under her wing, whose father has disappeared and mother ignores him. Meanwhile, Lisa gets picked on at school for being overweight and goes on a diet.